GRAMOZ -D Capsule

What is GRAMOZ‑D Capsule?

GRAMOZ‑D Capsule is a prescription gastro‑resistant, sustained‑release capsule that combines Rabeprazole 20 mg (proton pump inhibitor) with Domperidone 30 mg SR (prokinetic and antiemetic). It is used to relieve acidity, gas, heartburn, reflux, nausea and bloating associated with gastro‑esophageal reflux disease (GERD), acid peptic disorders and functional dyspepsia.​

Key Benefits

• Rabeprazole 20 mg reduces excess stomach acid, helping heal erosions and ulcers and easing heartburn, sour belching, chest discomfort and acid reflux.​

• Domperidone 30 mg SR enhances upper‑gut motility and has anti‑nausea action, which reduces bloating, early fullness, nausea and vomiting.​

Together, GRAMOZ‑D Capsule controls both acid and motility components of GERD and dyspepsia for broader symptom relief.​

Uses & Indications

Doctors prescribe GRAMOZ‑D Capsule SR for:​

• Gastro‑esophageal reflux disease (GERD), acid reflux and heartburn, including regurgitation and acid‑related chest pain.​

• Peptic ulcer disease and acid‑peptic disorders requiring potent acid suppression plus prokinetic support.​

• Dyspepsia and upper abdominal discomfort with complaints of bloating, gas, nausea and early satiety.​

Evaluation for alarm features such as weight loss, anaemia, difficulty swallowing or GI bleeding is essential before long‑term use.​

Dosage & Directions

The exact regimen should be set by a physician. Typical adult directions for Rabeprazole 20 mg + Domperidone 30 mg SR combinations:​

• One GRAMOZ‑D Capsule SR once daily, taken about 15–30 minutes before a main meal (often before breakfast), or as advised by the doctor.​

• Swallow the capsule whole with water; do not crush or chew it, to preserve enteric‑coated and sustained‑release properties.​

Treatment may last from a few weeks to several months depending on response and indication; do not stop suddenly without medical advice to avoid rebound acidity.​

Price & Packaging

• Brand: GRAMOZ‑D Capsule SR.​

• Strength: Rabeprazole 20 mg + Domperidone 30 mg sustained release.​

• Pack: Strip of 10 SR capsules, usually supplied in cartons for pharmacies and clinics.​

• Indicative price: Trade and online listings show MRPs around ₹140–₹150 per strip, with patient prices varying by retailer and discount.​

Always verify MRP, batch number, manufacturing date and expiry date on each strip before dispensing or use.​

Side Effects & Safety

GRAMOZ‑D Capsule SR is generally well tolerated, but side effects can occur. Commonly reported reactions include:​

• Diarrhoea, constipation, stomach pain, flatulence, dry mouth, nausea or vomiting.​

• Headache, dizziness, weakness, insomnia or back pain.​

Most of these are mild and transient, but persistent or severe symptoms should be reported to a doctor. Long‑term PPI use has been associated in some patients with vitamin B12 or magnesium deficiency, fractures and infections, so prolonged therapy should be periodically reviewed.​

Domperidone at higher or prolonged doses has been linked to QT‑interval prolongation and arrhythmia risk in susceptible patients, especially those with cardiac disease or on interacting drugs.​

Precautions & Contraindications

• Contraindicated in patients with known allergy to Rabeprazole, Domperidone or any excipient.​

• Avoid or use with caution in people with significant heart disease, known QT prolongation, electrolyte disturbances or those taking QT‑prolonging medicines.​

• Use carefully in moderate‑to‑severe liver impairment and significant renal dysfunction; monitoring or dose adjustment may be required.​

• Long‑term or high‑dose use in older adults should be considered only after weighing benefits and risks.​

• Pregnancy and breastfeeding use should be based on a risk–benefit assessment by the treating physician.​

Inform the doctor about all medicines including antifungals, antibiotics, antidepressants, antiarrhythmics and antipsychotics to minimise interaction risk.​

10 Frequently Asked Questions (FAQ)

1. What is GRAMOZ‑D Capsule used for?
It is used for GERD, acid reflux, heartburn, gas, bloating, nausea and indigestion where both acid suppression and motility improvement are needed.​

2. How does GRAMOZ‑D Capsule work?
Rabeprazole blocks the gastric proton pump to reduce acid, while Domperidone increases upper‑gut motility and blocks dopamine receptors to reduce nausea and vomiting.​

3. When should I take GRAMOZ‑D?
Take one capsule about 15–30 minutes before food, usually before breakfast, or as instructed by your doctor.​

4. How long does it take to feel relief?
Heartburn and indigestion often improve within a few days, but complete healing of esophagitis or ulcers may take several weeks.​

5. Can I take antacids along with GRAMOZ‑D?
Occasional antacids may be used for breakthrough symptoms if your doctor agrees, but frequent unsupervised combinations are not advised.​

6. Does GRAMOZ‑D Capsule cause drowsiness?
It can cause dizziness or drowsiness in some patients, so avoid driving or operating machinery until its effects on you are known.​

7. Is long‑term use of GRAMOZ‑D safe?
Long‑term use is sometimes needed in chronic GERD, but requires regular review for PPI‑related risks and Domperidone’s cardiac safety.​

8. Can GRAMOZ‑D be used in kidney or liver disease?
It should be used with caution; dose adjustment or alternative therapy may be needed in moderate‑to‑severe impairment.​

9. What should I do if I miss a dose?
Take it when remembered unless it is close to the next scheduled dose; do not double up to make up for a missed capsule.​

10. When should I seek urgent medical help?
Seek immediate care for chest pain suggesting heart disease, black or bloody stools, vomiting blood, severe abdominal pain, severe dizziness, palpitations or allergic reactions (rash, swelling, breathing difficulty).​

Quick Tips

• Take GRAMOZ‑D Capsule at the same time daily before food to maximise efficacy and maintain consistent symptom control.​

• Avoid late‑night heavy meals, lying down soon after eating, smoking, large caffeine intakes and alcohol, as these can worsen reflux.​

• Do not stop the medicine suddenly after long‑term use; discuss tapering or step‑down therapy with your doctor.​

Why Choose Ingram BioSciences?

GRAMOZ‑D Capsule belongs to Ingram BioSciences’ gastro‑hepato care range, which also includes GRAMOZ‑IT, OBGRAM, Eldgram, Bisgram and Pepto Bisgram. Ingram partners with WHO‑GMP–aligned units and provides clear disclaimers emphasising that its GI products are to be used under professional supervision, not as self‑medication.​

This focused GI portfolio and quality positioning support clinician trust in GRAMOZ‑D as a Rabeprazole 20 mg + Domperidone 30 mg SR option for reflux and dyspepsia.​

Customer Support & Ordering

For information on GRAMOZ‑D Capsule or other Ingram BioSciences products:​

• Manufacturer/Marketer: Ingram Biosciences Pvt Ltd.​

• Address: Office‑308, 3rd Floor, Living Style Mall, Jasola, New Delhi‑110025, India.​

• Phone / WhatsApp: +91 99997 81444; Mobile: +91 76690 11534.​

• Email: info@ingrambiosciences.in​

GRAMOZ‑D Capsule SR is available via hospitals, retail pharmacies, franchise partners and major online pharmacies; it must be used only on the prescription and supervision of a registered medical practitioner.