MIDGRAM 2.5 Tablet

What is MIDGRAM 2.5 Tablet?

MIDGRAM 2.5 Tablet contains Midodrine Hydrochloride 2.5 mg, a prodrug whose active metabolite (desglymidodrine) is an alpha‑1 adrenergic agonist. By tightening (constricting) blood vessels and increasing peripheral vascular resistance, it raises blood pressure, particularly when standing.​

Key Benefits

• Helps relieve dizziness, light‑headedness and fainting associated with chronic low blood pressure or orthostatic hypotension.​

• Improves standing blood pressure and functional capacity, allowing patients to carry out daily activities with fewer hypotensive episodes.​

Uses & Indications

Clinicians prescribe MIDGRAM 2.5 Tablet for:

• Orthostatic hypotension (sudden BP drop on standing) due to autonomic failure and related conditions, where symptoms persist despite non‑drug measures.​

• Symptomatic chronic low blood pressure in selected adults when other causes have been corrected (e.g., dehydration, medication‑induced hypotension).​

Specialist supervision (neurologist/cardiologist or internist experienced in orthostatic hypotension) is recommended.​

Dosage & Directions

Dose must be individualised and up‑titrated cautiously.​

• Usual starting dose: 2.5 mg three times daily during daytime hours.​

• Dose may be increased weekly based on response, up to a typical maintenance 5–10 mg three times daily, not exceeding the maximum recommended by the prescriber.​

Tablets are taken in daytime (e.g., morning, midday, late afternoon), at roughly 4‑hour intervals, and should not be taken close to bedtime to reduce risk of high BP while lying down (supine hypertension). They may be taken with or without food.​

Price & Packaging

Indian listings show MIDGRAM 2.5 Tablet (Ingram Biosciences) with an MRP of around ₹41–₹45 per 10‑tablet strip, with Medkart quoting approximately ₹35.06 after discount. Some trade portals quote about ₹350 per strip as a bulk/PCD rate for multiple strips.​

The product is supplied as blister strips of 10 tablets in branded cartons with composition, batch details and expiry clearly printed.​

Side Effects & Safety

Most side effects are mild and improve as the body adjusts. Common adverse effects include:​

• Scalp tingling, piloerection (goosebumps), itching or rash, abdominal discomfort, nausea and headache.​

• Supine hypertension and urinary problems such as difficulty in urination or urinary retention.​

Serious but less common side effects include chest pain, rapid or irregular heartbeat, severe dizziness, breathlessness, severe headache, blurred vision and fainting, which require urgent medical attention.​

Precautions & Contraindications

MIDGRAM 2.5 Tablet is not advised in patients with:

• Allergy to midodrine or excipients, severe heart disease, very slow heart rate, uncontrolled hypertension or severe arterial occlusive disease.​

• Enlarged prostate, urinary retention, pheochromocytoma, acute or severe kidney disease, hyperthyroidism, diabetic retinopathy with poor vision, or narrow‑angle glaucoma.​

Careful monitoring is required in patients with existing cardiac disease, kidney impairment or those on other BP‑raising drugs.​

10 Frequently Asked Questions (FAQ)

1. What is MIDGRAM 2.5 Tablet used for?
It is used to treat orthostatic hypotension and symptomatic low blood pressure that cause dizziness or fainting on standing.​

2. How does MIDGRAM 2.5 work?
Its active metabolite stimulates alpha‑1 receptors in blood vessels, tightening them and raising blood pressure.​

3. When should I take MIDGRAM 2.5?
Typically three times a day during daytime; avoid taking it within about 4 hours of bedtime to reduce high BP while lying down.​

4. How soon will I feel better?
Some improvement in dizziness may be seen within days, but dose titration and monitoring over weeks are often needed.​

5. Can MIDGRAM 2.5 cause high BP when lying down?
Yes, supine hypertension is a known risk; blood pressure should be monitored both sitting/standing and lying.​

6. Is MIDGRAM 2.5 safe for the heart?
It should be used cautiously in heart disease; chest pain, fast or irregular heartbeat or breathlessness need immediate review.​

7. Can it cause urinary problems?
Yes, difficulty in urination and urinary retention can occur, especially in men with prostate enlargement.​

8. How long can I use MIDGRAM 2.5?
Duration depends on the underlying cause and response; treatment should be reviewed regularly by the specialist.​

9. Can I take it with other BP medicines?
Combinations need careful planning; it should not be combined with other pressor agents without close monitoring.​

10. Is MIDGRAM 2.5 suitable for children?
Use in children is not routine and must be specifically decided by a paediatric specialist.​

Quick Tips

• Take MIDGRAM 2.5 only during daytime and avoid lying flat soon after a dose.​

• Continue non‑drug measures such as slow position changes, compression stockings, fluid and salt (if advised) to support blood pressure.​

• Monitor blood pressure lying and standing as your doctor advises; report severe headache, chest pain, vision changes or urinary difficulty promptly.​

Why Choose Ingram BioSciences?

MIDGRAM 2.5 sits within Ingram’s Gastro & Hepato Care basket, alongside URNOZ, SYLNOZ, GRAMOZ BC and HEPAROL, giving physicians a broader autonomic and liver‑care toolkit. Ingram operates from Jasola, New Delhi, with clear doctor‑focused information and pan‑India trade and PCD relationships.​

This makes MIDGRAM 2.5 a credible midodrine 2.5 mg option for clinics managing complex low BP and autonomic dysfunction.​

Customer Support & Ordering

For enquiries and ordering related to MIDGRAM 2.5 Tablet:

• Company: Ingram Biosciences Pvt Ltd.​

• Delhi Office: Office‑308, 3rd Floor, Living Style Mall, Jasola, New Delhi – 110025, India.​

• Phone / WhatsApp: +91 99997 81444; Mobile: +91 76690 11534.​

• Email: info@ingrambiosciences.in​

MIDGRAM 2.5 Tablet is available via hospitals, retail chemists, PCD/franchise partners and major e‑pharmacies and must be used strictly on the prescription of a registered medical practitioner.​