SYLNOZ 400 Tablet

What is SYLNOZ 400 Tablet?

SYLNOZ 400 Tablet contains Ademetionine (1,4‑Butane Disulfonate SD4) 400 mg, a form of S‑adenosylmethionine (SAMe). Ademetionine participates in methylation reactions and glutathione synthesis, which support liver detoxification and may influence mood and joint health.​

Key Benefits

• Helps improve liver function and bile flow in various liver diseases, particularly cholestatic conditions.​

• Provides adjunctive benefit in depression and osteoarthritis, with potential improvement in mood and joint pain in selected patients.​

Uses & Indications

Clinicians use SYLNOZ 400 Tablet (ademetionine 400 mg) for:

• Chronic liver disease and intrahepatic cholestasis, including alcohol‑related and non‑alcoholic fatty liver disease, to improve liver enzymes and symptoms.​

• As an adjunct in depressive disorders and osteoarthritis where SAMe’s neuromodulatory and chondroprotective actions are considered beneficial.​

It should only be used under medical supervision; indications and duration vary by patient.​

Dosage & Directions

Dose must be individualized by the treating specialist. Typical ademetionine oral doses reported are:​

• Liver disease: around 400–800 mg/day (often 400 mg once or twice daily), sometimes titrated up, depending on severity.​

• Depression / osteoarthritis: regimens can range from 400–1600 mg/day in divided doses, with careful monitoring.​

Tablets are usually taken on an empty stomach or as directed; dose adjustments or step‑down from parenteral therapy may be used in hospital protocols. Patients must not alter or stop doses without medical advice.​

Price & Packaging

On Ingram’s site, SYLNOZ 400 Tablet is listed with an original price of ₹800 and a current price of ₹680 (likely per 10‑tablet strip). Other pharmacy and trade listings show similar ademetionine 400 mg tablets with per‑strip prices reflecting a premium hepatology product segment.​

Side Effects & Safety

Common side effects seen with Sylnoz 400 (and ademetionine in general) include:

• Nausea, diarrhoea and abdominal discomfort, usually mild and self‑limiting.​

• Headache, insomnia or skin rash in some patients.​

Most effects are temporary; persistent or severe symptoms should prompt review and possible dose adjustment or discontinuation.​

Precautions & Contraindications

• Use with caution in patients with bipolar disorder, as SAMe may rarely exacerbate mood swings or trigger hypomania.​

• Caution in severe liver or kidney impairment, elderly patients, and those on multiple interacting medicines; specialist supervision is advised.​

• Pregnancy and breastfeeding use should be based on risk–benefit assessment; data are limited, so it is generally avoided unless clearly needed.​

Alcohol use should be minimized as it adds further stress to the liver and can blunt therapeutic benefit.​

10 Frequently Asked Questions (FAQ)

1. What is SYLNOZ 400 Tablet used for?
It is primarily used for chronic liver diseases and intrahepatic cholestasis and, in some cases, as adjunct therapy in depression and osteoarthritis.​

2. Is SYLNOZ 400 a liver tonic or a medicine?
It is a prescription medicine containing ademetionine (SAMe), not a general “tonic,” and should be taken only under medical advice.​

3. How long does it take to show liver benefits?
Improvement in symptoms and liver tests may be seen over weeks; duration depends on the underlying condition and response.​

4. Can Sylnoz 400 improve mood?
Ademetionine has evidence as an adjunct in depression; any mood benefit must be monitored by a psychiatrist or physician.​

5. Does Sylnoz 400 help joint pain?
Some studies support SAMe in osteoarthritis for pain relief and function; it is usually used alongside standard joint therapies.​

6. What are the common side effects?
Nausea, diarrhoea, abdominal pain, headache, insomnia and mild rash are among the common side effects.​

7. Is it safe with other liver medicines like UDCA?
Doctors sometimes combine ademetionine with agents like ursodeoxycholic acid; combinations must be individualized and monitored.​

8. Can people with bipolar disorder take it?
Use is cautious because ademetionine may rarely trigger manic symptoms; psychiatric history must be disclosed to the prescriber.​

9. Do I need regular tests while on Sylnoz 400?
Yes, liver function tests and clinical assessment are usually repeated to track response and safety.​

10. Is lifelong therapy required?
Duration varies; some patients need medium‑term courses, others longer, depending on disease and specialist judgement.​

Quick Tips

• Take SYLNOZ 400 Tablet exactly as prescribed; do not increase or skip doses on your own.​

• Inform your doctor about any history of mood disorders, all concurrent medicines and any new symptoms like severe diarrhoea, insomnia or mood changes.​

• Avoid alcohol and maintain a liver‑friendly lifestyle (balanced diet, weight control, limited hepatotoxic drugs) to maximise benefit.​

Why Choose Ingram BioSciences?

SYLNOZ 400 is part of Ingram BioSciences’ Gastro & Hepato Care segment, alongside products like BISGRAM, HEPAROL 400, URNOZ and GRAMOZ‑GT500 for comprehensive digestive and liver support. Ingram operates from Jasola, New Delhi, using WHO‑GMP‑aligned partners and clearly states that its product information is for physicians, reinforcing a prescriber‑centric approach.​

This makes Sylnoz 400 a credible ademetionine 400 mg option in Indian hepatology and gastroenterology practice.​

Customer Support & Ordering

For medical or business enquiries about SYLNOZ 400 Tablet:

• Company: Ingram Biosciences Pvt Ltd.​

• Delhi Office: Office‑308, 3rd Floor, Living Style Mall, Jasola, New Delhi – 110025, India.​

• Phone / WhatsApp: +91 99997 81444; Mobile: +91 76690 11534.​

• Email: info@ingrambiosciences.in​

SYLNOZ 400 Tablet is available via hospitals, retail chemists, PCD/franchise partners and major e‑pharmacy platforms, and must be used only on the prescription of a registered medical practitioner.