URNOZ-300 Tablet

What is Urnoz 300 Tablet?

Urnoz 300 Tablet provides Ursodeoxycholic Acid (UDCA) 300 mg per film‑coated tablet. UDCA works by reducing cholesterol saturation in bile, protecting liver cells from toxic bile acids and improving bile flow.​

Key Benefits

• Helps dissolve small to medium cholesterol gallstones in patients with a functioning gallbladder, providing a non‑surgical option in selected cases.​

• Treats cholestatic liver diseases, including primary biliary cirrhosis/cholangitis and non‑alcoholic or alcoholic fatty liver disease, by improving liver enzymes and bile flow.​

Uses & Indications

Doctors prescribe Urnoz 300 Tablet (ursodeoxycholic acid 300 mg) for:

• Cholesterol gallstones in patients where surgery is high‑risk or needs to be avoided.​

• Primary biliary cirrhosis/cholangitis (PBC) and other chronic cholestatic liver diseases to improve liver function and symptoms like pruritus.​

• Supportive treatment in non‑alcoholic fatty liver disease (NAFLD) and alcoholic fatty liver disease, as part of lifestyle and comprehensive therapy.​

Indications and duration are always individualized by a hepatologist or gastroenterologist.​

Dosage & Directions

Dosing depends on body weight and indication and must be decided by the treating physician.​

• For gallstones, a common total daily dose is 8–10 mg/kg/day, often split into 2–3 doses, with one dose usually taken at bedtime.​

• Urnoz 300 Tablets are typically taken after meals with water or milk, at evenly spaced times (for example, morning, afternoon, evening) as advised.​

Therapy may need months to years; regular monitoring of liver enzymes and ultrasound assessment is recommended.​

Price & Packaging

Ingram’s site lists URNOZ‑300 Tablet at an original price of about ₹380 with a current price near ₹323 for a 10‑tablet strip. Other pharmacy listings show similar MRP with occasional discounts, keeping it in the premium hepatology segment.​

Urnoz 300 is supplied as Alu‑Alu blister strips (10 tablets) in a printed carton with strength, composition, batch number, manufacturing and expiry details.​

Side Effects & Safety

Ursodeoxycholic acid is generally safe and well tolerated but can cause:

• Common side effects: abdominal pain, abdominal discomfort, diarrhoea, nausea, rash, itching, headache, hair loss, back pain, flatulence, fatigue and dyspepsia.​

• Less commonly, respiratory or urinary infections, joint pain, muscle pain and insomnia have been reported.​

If diarrhoea is significant, the doctor may reduce the dose or discontinue therapy; long‑term use requires periodic monitoring of liver enzymes.​

Precautions & Contraindications

• Contraindicated in acute inflammation of the gallbladder or bile ducts, complete biliary obstruction, non‑functional gallbladder, radiopaque (calcified) stones and certain advanced liver decompensations.​

• Use cautiously in patients with variceal bleeding, ascites, hepatic encephalopathy or severe cirrhosis, under specialist supervision only.​

• Avoid concomitant aluminium‑containing antacids, cholestyramine or colestipol near UDCA dosing, as they can reduce absorption; spacing doses is advised.​

Pregnant or breastfeeding women should only use UDCA after discussing risks and benefits with their doctor.​

10 Frequently Asked Questions (FAQ)

1. What is Urnoz 300 Tablet used for?
It is used to dissolve certain cholesterol gallstones and to treat cholestatic liver diseases like primary biliary cirrhosis and fatty liver‑related cholestasis.​

2. How long does it take to dissolve gallstones?
Gallstone dissolution can take several months to over a year; not all stones respond, and ultrasound monitoring is needed.​

3. Will my gallstones come back after stopping Urnoz 300?
Gallstones can recur, especially if risk factors persist; lifestyle changes and risk factor control are important.​

4. When should I take Urnoz 300?
It is usually taken after meals with water or milk, with one dose often recommended at bedtime when used for gallstone dissolution.​

5. Is Urnoz 300 safe for long‑term use?
Long‑term use is common in PBC and chronic cholestasis, but requires regular liver function monitoring and medical supervision.​

6. Does Urnoz 300 cause weight gain?
Weight gain has been reported rarely, particularly in patients with chronic cholestatic liver disease; any rapid weight change should be discussed with the doctor.​

7. Can I take antacids with Urnoz 300?
Antacids containing aluminium and bile acid‑binding resins can reduce UDCA absorption and should be separated by several hours or avoided as advised.​

8. Is Urnoz 300 useful in non‑alcoholic fatty liver disease?
UDCA may be used in some NAFLD patients with cholestatic features, but lifestyle measures remain the cornerstone of treatment.​

9. What tests are needed while on Urnoz 300?
Liver enzymes and bilirubin are usually checked monthly for the first three months and then every six months or as advised.​

10. Can Urnoz 300 be used during pregnancy?
UDCA is used in some pregnancy‑related cholestasis under specialist care, but pregnancy use in other settings must be carefully weighed by the obstetrician and hepatologist.​

Quick Tips

• Take Urnoz 300 exactly as prescribed; do not stop abruptly without consulting your doctor.​

• Follow a healthy diet, regular exercise and strict alcohol avoidance to support liver health and improve outcomes.​

• Seek medical help if you notice severe abdominal pain, black stools, jaundice worsening or persistent diarrhoea.​

Why Choose Ingram BioSciences?

Urnoz 300 sits within Ingram BioSciences’ dedicated Gastro & Hepato Care portfolio, alongside products like HEPAROL 400, GRAMOZ‑GT500, SYLNOZ‑400 and GRAMOZ‑BC, offering a comprehensive liver care basket. Ingram operates from Jasola, New Delhi, working with quality‑focused manufacturing partners and prominently displaying physician‑centric disclaimers across its product pages.​

This positioning makes Urnoz 300 a credible UDCA 300 mg option for Indian hepatologists, gastroenterologists and physicians.​

Customer Support & Ordering

For enquiries and ordering related to Urnoz 300 Tablet:

• Company: Ingram Biosciences Pvt Ltd.​

• Delhi Office: Office‑308, 3rd Floor, Living Style Mall, Jasola, New Delhi – 110025, India.​

• Phone / WhatsApp: +91 99997 81444; Mobile: +91 76690 11534.​

• Email: info@ingrambiosciences.in​

Urnoz 300 is available via hospitals, retail chemists, PCD/franchise partners and leading e‑pharmacies and should be used only on the prescription of a registered medical practitioner.